Atletico Madrid secured a comfortable 2-0 Champions League victory over Manchester United on Tuesday, increasing the pressure on visiting manager Michael Carrick.
Pablo Barrios opened the scoring inside the first minute for Diego Simeone's side. In the 74th minute, United's Leny Yoro was sent off, leaving the visitors further exposed, and Ademola Lookman sealed the win for the hosts in Madrid.
It was United's longest domestic start in 40 years, and the group-stage defeat on Spanish soil delivered another blow, with the club now winless in five matches across all competitions.
Carrick handed Carlos Baleba his first competitive start since his summer arrival from Brighton, while shifting captain Bruno Fernandes to the right flank.
Atletico were without captain Koke following the death of his mother, and Simeone gave Julian Alvarez his first start of the season at the Metropolitano after the forward's attempts to leave over the summer.
Before kickoff, Atletico fans unfurled a banner reading "Protect what we love." The hosts took the lead after just 50 seconds.
Alex Baena looked to play the ball in behind the United defense before squaring for Barrios, and Ayden Heaven was unable to stop the midfielder's shot from crossing the line.
Bryan Mbuemo might have equalized for the visitors, rounding Cristian Romero but dragging his effort wide of the post.
Alejandro Grimaldo came agonizingly close to making it 2-0 with a free kick that struck the junction of post and crossbar.
The hosts thought they had a second when Johnny Cardoso finished neatly from the edge of the box before the break, but the goal was disallowed after VAR showed the ball had struck Marcos Llorente's hand in the build-up.
Alvarez, who has yet to score for Atletico this season, hit the post early in the second half.
United pushed forward, Fernandes lifting a chip narrowly over the bar before the Portuguese midfielder struck the crossbar from the left side of the box after a corner routine.
But the three-time European champions were dealt a setback when defender Yoro was sent off after a VAR review for a foul on Canada forward Jonathan David as the last man.
That opened the door for Atletico's second. David was denied by goalkeeper Senne Lammens, but London-born Nigeria forward Lookman was on hand to tap in the rebound in the 79th minute.
Carrick withdrew playmaker Fernandes to prepare for the weekend trip to Leeds in the Premier League, where the team needs to improve its form. Atletico goalkeeper Jan Oblak saved a late effort from substitute Matheus Cunha, but United could not find a way back.
Simeone's side claimed their first points after an opening defeat to Liverpool.
